The
dissolution rate of drug from tablet is affected by its active
ingredient’s surface area and consequently, affects in oral
bioavailability of the product. The development of formulations
containing poorly-water-soluble drugs for oral delivery can be achieved
by improving their dissolution. It has been found that increasing the
available surface area by reducing the particle size can often markedly
improve dissolution rates and lead to...
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SOURCE: PHARMATUTOR.ORG
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