Delivery of the drug via skin would provide a useful alternative to
oral route and important site of drug application for local and
systemic effects with minimum undesirable side effects. Skin penetration
techniques have been developed to improve bioavailability and enhance
the range of drugs for which transdermal delivery is a viable option.
The permeation of drug through skin can be enhanced by chemical
penetration enhancers. The present review article includes the
classification of permeation enhancers and their mechanism of action;
thus it will help in the selection of suitable penetration enhancer for
improving the permeation of poorly absorbed drugs via transdermal route.
SOURCE: PHARMATUTOR.ORG
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