A REVIEW ON DETERMINATION OF PRESERVATIVES IN FOOD STUFFS BY DIFFERENT ANALYTICAL METHODS

Majority of instances of food spoilage can be attributed to the attack by pathogens (disease-causing microorganisms ) such as bacteria and molds,  Different methods that had been devised for preserving foods are all designed to reduce or eliminate to the causative agents.  The food preservation refers to techniques

READ MORE: 
http://www.pharmatutor.org/articles/review-on-determination-preservatives-food-stuffs-different-analytical-methods



SOURCE: PHARMATUTOR.ORG

SUBJECT RECRUITMENT AND RETENTION AT THE TRIAL SITE

Achieving clinical trial research participant recruitment and retention is essential for conducting a successful trial. Adequate enrollment provides a base for projected participant retention, resulting in evaluative patient data. Obtaining final evaluative data is dependent on successful patient and principal investigator retention. Patients cannot be retained without an initial pool of enrolled volunteers.

READ MORE: 

http://www.pharmatutor.org/articles/subject-recruitment-retention-trial-site

SOURCE: PHARMATUTOR.ORG

A REVIEW : CHEMICAL PENETRATION ENHENCERS FOR TRANSDERMAL DRUG DELIVERY SYSTEMS

Delivery of the drug via skin would provide a useful alternative to oral route and important site of drug application for local and systemic effects with minimum undesirable side effects. Skin penetration techniques have been developed to improve bioavailability and enhance the range of drugs for which transdermal delivery is a viable option. The permeation of drug through skin can be enhanced by chemical penetration enhancers. The present review article includes the classification of permeation enhancers and their mechanism of action; thus it will help in the selection of suitable penetration enhancer for improving the permeation of poorly absorbed drugs via transdermal route.

Find at: http://www.pharmatutor.org/articles/review-chemical-penetration-enhencers-transdermal-drug-delivery-systems

SOURCE: PHARMATUTOR.ORG

TRANSDERMAL A NOVEL DRUG DELIVERY SYSTEM

Transdermal drug delivery systems (TDDS) are dosage forms involves drug transport to viable epidermal and or dermal tissues of the skin for local therapeutic effect while a very major fraction of drug is transported into the systemic blood circulation. The adhesive of the transdermal drug delivery system is critical to the safety...

READ MORE: 

http://www.pharmatutor.org/articles/transdermal-novel-drug-delivery-system

SOURCE: PHARMATUTOR.ORG

ESTIMATION OF OXIDATIVE STRESS AND ANTIOXIDANT STATUS IN TYPE II DIABETIC PATIENTS

Diabetes mellitus is a group of metabolic disorders characterized by hyperglycemia and abnormalities in carbohydrate, fat and protein metabolism. It results from defects in insulin secretion, insulin sensitivity or both. Oxidative stress may play an important role in the itiology of diabetes and Diabetic complications. So, during Diabetes hyperglycemia causes increased production of free radical especially reactive oxygen species(ROS) for all tissues from glucose auto-oxidation and protein glycosylation.

READ MORE: 

http://www.pharmatutor.org/articles/estimation-oxidative-stress-antioxidant-status-in-type-diabetic-patients

SOURCE: PHARMATUTOR.ORG

FIBRODYSPLASIA OSSIFICANS PROGRESSIVA

Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disorder of the connective tissue characterized by progressive disability as a result of extensive extra skeletal enchondral bone formation and malformed big toes which are often monophalangic. Occasional features include short thumbs, fifth finger clinodactyly, malformed cervical vertebrae and mild mental retardation. Beginning during childhood, FOP progressively immobilizes all the joints through adult life, rendering movement impossible. Currently, there is no effective prevention or cure for this debilitating disease.

READ MORE: 

http://www.pharmatutor.org/articles/fibrodysplasia-ossificans-progressiva

SOURCE: PHARMATUTOR.ORG

EVIDENCE-BASED MEDICINE TO PERSONALIZED MEDICINE – A PROSPECTIVE

Evidence-based medicine (EBM) is the process of systematically reviewing, appraising and using clinical research findings to aid the delivery of optimum clinical care to patients. It is a method of healthcare decision-making that intends to combine the most reliable scientific information with individual expertise and patient preferences in order to offer the optimal diagnostic and therapeutic option for the patient. On the other hand, pharmacogenomics is a whole genome application that examines the single gene interactions with drugs. In recent years, the term personalized medicine has been introduced to represent an approach considering differences among individual patients. In modern medicine, the most important sources of evidence are clinical trials using epidemiological methods, and molecular biological and genetic methods characterizing individual patients.

READ MORE: 

http://www.pharmatutor.org/articles/evidence-based-medicine-personalized-medicine-prospective

SOURCE: PHARMATUTOR.ORG