SUBJECT RECRUITMENT AND RETENTION AT THE TRIAL SITE

Achieving clinical trial research participant recruitment and retention is essential for conducting a successful trial. Adequate enrollment provides a base for projected participant retention, resulting in evaluative patient data. Obtaining final evaluative data is dependent on successful patient and principal investigator retention. Patients cannot be retained without an initial pool of enrolled volunteers.

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http://www.pharmatutor.org/articles/subject-recruitment-retention-trial-site

SOURCE: PHARMATUTOR.ORG

A REVIEW : CHEMICAL PENETRATION ENHENCERS FOR TRANSDERMAL DRUG DELIVERY SYSTEMS

Delivery of the drug via skin would provide a useful alternative to oral route and important site of drug application for local and systemic effects with minimum undesirable side effects. Skin penetration techniques have been developed to improve bioavailability and enhance the range of drugs for which transdermal delivery is a viable option. The permeation of drug through skin can be enhanced by chemical penetration enhancers. The present review article includes the classification of permeation enhancers and their mechanism of action; thus it will help in the selection of suitable penetration enhancer for improving the permeation of poorly absorbed drugs via transdermal route.

Find at: http://www.pharmatutor.org/articles/review-chemical-penetration-enhencers-transdermal-drug-delivery-systems

SOURCE: PHARMATUTOR.ORG

TRANSDERMAL A NOVEL DRUG DELIVERY SYSTEM

Transdermal drug delivery systems (TDDS) are dosage forms involves drug transport to viable epidermal and or dermal tissues of the skin for local therapeutic effect while a very major fraction of drug is transported into the systemic blood circulation. The adhesive of the transdermal drug delivery system is critical to the safety...

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http://www.pharmatutor.org/articles/transdermal-novel-drug-delivery-system

SOURCE: PHARMATUTOR.ORG

ESTIMATION OF OXIDATIVE STRESS AND ANTIOXIDANT STATUS IN TYPE II DIABETIC PATIENTS

Diabetes mellitus is a group of metabolic disorders characterized by hyperglycemia and abnormalities in carbohydrate, fat and protein metabolism. It results from defects in insulin secretion, insulin sensitivity or both. Oxidative stress may play an important role in the itiology of diabetes and Diabetic complications. So, during Diabetes hyperglycemia causes increased production of free radical especially reactive oxygen species(ROS) for all tissues from glucose auto-oxidation and protein glycosylation.

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http://www.pharmatutor.org/articles/estimation-oxidative-stress-antioxidant-status-in-type-diabetic-patients

SOURCE: PHARMATUTOR.ORG