FIBRODYSPLASIA OSSIFICANS PROGRESSIVA

Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disorder of the connective tissue characterized by progressive disability as a result of extensive extra skeletal enchondral bone formation and malformed big toes which are often monophalangic. Occasional features include short thumbs, fifth finger clinodactyly, malformed cervical vertebrae and mild mental retardation. Beginning during childhood, FOP progressively immobilizes all the joints through adult life, rendering movement impossible. Currently, there is no effective prevention or cure for this debilitating disease.

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http://www.pharmatutor.org/articles/fibrodysplasia-ossificans-progressiva

SOURCE: PHARMATUTOR.ORG

EVIDENCE-BASED MEDICINE TO PERSONALIZED MEDICINE – A PROSPECTIVE

Evidence-based medicine (EBM) is the process of systematically reviewing, appraising and using clinical research findings to aid the delivery of optimum clinical care to patients. It is a method of healthcare decision-making that intends to combine the most reliable scientific information with individual expertise and patient preferences in order to offer the optimal diagnostic and therapeutic option for the patient. On the other hand, pharmacogenomics is a whole genome application that examines the single gene interactions with drugs. In recent years, the term personalized medicine has been introduced to represent an approach considering differences among individual patients. In modern medicine, the most important sources of evidence are clinical trials using epidemiological methods, and molecular biological and genetic methods characterizing individual patients.

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http://www.pharmatutor.org/articles/evidence-based-medicine-personalized-medicine-prospective

SOURCE: PHARMATUTOR.ORG

LIPOSOMES AN OVERVIEW– A NOVEL TREND IN THE DRUG DELIVERY

Liposomes are result of self assembly of phospholipid in an aqueous media resulting in closed bilayered structures. Liposomes are one of unique drug delivery system which can be use in controlling and targeting drug delivery system. Liposomes are generally classified based upon structure, method of preparation, composition and application, conventional liposome, and specialty liposome. Liposomes are formulated and processed to differ in size, composition, charge and lamellarity, depending upon method of preparation either active loading technique or passive loading technique. The prepared liposomes are characterized for visual appearance, liposomal size distribution, lamillarity, liposome stability, entrapped volume and surface charges. Different marketed formulations are available in market for liposomes. The liposomes have many applications which increase its importance over other formulations.

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http://www.pharmatutor.org/articles/liposomes-overview-novel-trend-drug-delivery

SOURCE: PHARMATUTOR.ORG

A REVIEW ON IMPLANTABLE DRUG DELIVERY SYSTEM

There was a need for delivery systems that could maintain a steady release of drug to the specific site of action. Therefore, drug delivery systems were developed to optimize the  therapeutic properties of drug products and render them more safe, effective, and reliable. In comparison with many of the other drug...

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http://www.pharmatutor.org/articles/review-implantable-drug-delivery-system



SOURCE: PHARMATUTOR.ORG